Product Description:
Stearoylethanolamide (SEA) has been shown to decrease food intake independent of PPAR and without changing hematochemical parameters such as glucose and triglyceride levels or leptin (a hormone involved with satiety) expression. The appetite decreasing effect of SEA was associated with a reduction in liver stearoyl-CoA desaturase-1 (SCD-1) mRNA expression. SCD-1 is the rate-limiting enzyme in the biosynthesis of monounsaturated fats and its reduction is believed to lead to increased fatty acid oxidation and decreased lipogenesis in skeletal muscle and the liver.
Recommended Dosage:
As a dietary supplement, take 1250mg of SEA (yielding 250mg of Active SEA) 1-2 times per day.